Research Blog

Like coffee and chromatography? Fun fact: brewing a perfect espresso is a lot like doing chromatography with broken fraction collector, where you only have one tube to collect extract. Good espresso requires some tuning, but let’s simplify for clarity. For a double espresso, take 14 g of ground coffee and extract it with a 1:2 brew ratio – that is, 28 g of water – over 30 seconds. This corresponds to a flow rate of roughly 60 mL/min. Assuming a homogeneous distribution of cof

I was repeatedly asked, "Still doing crystallography?" One week of work yielded this beautifully bound drug molecule. Please remember to choose the right tool for the task - don't get indoctrinated. Structural biology techniques are not interchangeable, each has its own scope and strengths. I have often encountered academic research groups, that look for scientific questions based on the technique that they comfortable to use. During my PhD and PostDoc I often needed a new te

AlphaFold3 represents a significant leap in the field of computational biology with its ability to predict 3D protein structures....